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Article

Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality.

The Journal of biological chemistry - 19 May 2000

Zhu Y, Qi C, Jia Y, Nye J S, Rao M S, Reddy J K

Abstract excerpt

We previously isolated and identified peroxisome proliferator-activated receptor (PPAR)-binding Protein (PBP) as a coactivator for PPARgamma. PBP has recently been identified as a component of the multiprotein complexes such as TRAP, DRIP, and ARC that appear to play an important role in the transcriptional activation by several transcriptional factors including nuclear receptors. To assess the biological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10747854
DOI: 10.1074/jbc.C000121200

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ARC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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