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Article

Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice.

Developmental biology - 1 Jul 2014

Vapola Miia H, Rokka Aare, Sormunen Raija T, Alhonen Leena, Schmitz Werner, Conzelmann Ernst, Wärri Anni, Grunau Silke, Antonenkov Vasily D, Hiltunen J Kalervo

Abstract excerpt

To understand the functional role of the peroxisomal membrane channel Pxmp2, mice with a targeted disruption of the Pxmp2 gene were generated. These mice were viable, grew and bred normally. However, Pxmp2(-/-) female mice were unable to nurse their pups. Lactating mammary gland epithelium displa...

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PMID: 24726525
DOI: 10.1016/j.ydbio.2014.03.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24726525-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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