Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development.

Molecular endocrinology (Baltimore, Md.) - 1 Sept 2004

Shi Heidi Y, Lydon John P, Zhang Ming

Abstract excerpt

Progesterone and PR are mainly thought to affect tertiary ductal side branching and alveologenesis in late stage of mammary gland development. Here, we present evidence that they also play a role in early ductal development. This conclusion derived from our analysis of maspin heterozygous (Mp+/-) mice that showed defective ductal development at puberty. The defect was due to a reduced systemic level of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Tumor Suppressor
Share to Mammary Glands, Animal
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mifepristone

Share to Ovariectomy

Share to Progesterone

Share to Proteins

Share to Serpins

Source

Identifiers

PMID: 15178746
DOI: 10.1210/me.2004-0052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development.PMID 15178746Read ↗

Revealing Progesterone's Role in Uterine and Mammary Gland Biology: Insights from the MouseSemantic proximity Read ↗

Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms.Semantic proximity Read ↗

A reappraisal of progesterone action in the mammary gland.Semantic proximity Read ↗

Reproductive phenotpes of the progesterone receptor null mutant mouse.Semantic proximity Read ↗

Cre-mediated recombination in cell lineages that express the progesterone receptor.Semantic proximity Read ↗

Null mutation of peroxisome proliferator-activated receptor-interacting protein in mammary glands causes defective mammopoiesis.Semantic proximity Read ↗

Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?Semantic proximity Read ↗

Endocrine defects in mice carrying a null mutation for the progesterone receptor gene.Semantic proximity Read ↗

Strain-Specific Differences in the Mechanisms of Progesterone Regulation of Murine Mammary Gland DevelopmentSemantic proximity Read ↗

Impaired mammary gland development in Cyl-1(-/-) mice during pregnancy and lactation is epithelial cell autonomous.Semantic proximity Read ↗

Ventral prostate and mammary gland phenotype in mice with complete deletion of the ERβ gene.Semantic proximity Read ↗

Research Resource: Progesterone Receptor Targetome Underlying Mammary Gland Branching MorphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.