Article
APOE polymorphism affects episodic memory among non demented elderly subjects.
Experimental gerontology - 1 Mar 2009
De Blasi Simona, Montesanto Alberto, Martino Cinzia, Dato Serena, De Rango Francesco, Bruni Amalia C, Mari Vincenzo, Feraco Emidio, Passarino Giuseppe
Abstract excerpt
The APOE epsilon4 allele has been associated with a number of neurodegenerative disorders e.g. Alzheimer's disease. Inconsistent results have been obtained for cognitive decline in 'normal' aging. We investigated whether specific aspects of cognitive decline were associated with APOE epsilon4 among 620 'healthy' elderly subjects living in Calabria, southern Italy. MMSE scores ranged from 11 to 30. A lower MMSE...
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