Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOE-epsilon4 is associated with memory decline in cognitively impaired elderly.

Neurology - 11 Apr 2000

Dik M G, Jonker C, Bouter L M, Geerlings M I, van Kamp G J, Deeg D J

Abstract excerpt

OBJECTIVE: To investigate whether the association between APOE-epsilon4 and memory decline is modified by baseline cognition and age in a population-based elderly sample. METHODS: The study sample consisted of 1,243 subjects, 62 to 85 years old, with a Mini-Mental State Examination (MMSE) score between 21 and 30 and known APOE phenotypes. Memory performance was measured with an abbreviated Auditory Verbal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Apolipoprotein E4
Share to Cognition Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Comorbidity

Share to Educational Status

Share to Memory Disorders

Share to Netherlands

Share to Sex Distribution

Source

Identifiers

PMID: 10751265
DOI: 10.1212/wnl.54.7.1492

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOE-epsilon4 is associated with memory decline in cognitively impaired elderly.PMID 10751265Read ↗

Apolipoprotein epsilon4 allele status, depressive symptoms, and cognitive decline in middle-aged and elderly persons without dementia.Semantic proximity Read ↗

The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults.Semantic proximity Read ↗

Longitudinal Modeling of Age-Related Memory Decline and the<i>APOE</i>ε4 EffectSemantic proximity Read ↗

Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.Semantic proximity Read ↗

Accelerated memory decline in Alzheimer's disease with apolipoprotein epsilon4 allele.Semantic proximity Read ↗

Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults.Semantic proximity Read ↗

Memory complaints and APOE-epsilon4 accelerate cognitive decline in cognitively normal elderly.Semantic proximity Read ↗

The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.Semantic proximity Read ↗

Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 affects new learning in cognitively normal individuals at risk for Alzheimer's disease.Semantic proximity Read ↗

The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period.Semantic proximity Read ↗

The relation between APOE status and neuropsychological memory test performance: an analysis of the Canadian Study of Health and Aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.