Article
High apolipoprotein E epsilon 4 allele frequency in age-related memory decline.
Annals of neurology - 1 Apr 1996
Blesa R, Adroer R, Santacruz P, Ascaso C, Tolosa E, Oliva R
Abstract excerpt
Many studies have demonstrated a strong association between the presence of one or two epsilon 4 alleles and Alzheimer's disease (AD), although few data are available on the apolipoprotein E (APOE) epsilon 4 frequencies at the preclinical stages of AD. Thus, with a view to determining whether APOE genotyping could be useful in the early detection of AD, we determined the Apoe allele frequencies in patients with...
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