Article
The dynamics of mutations associated with anti-malarial drug resistance in Plasmodium falciparum.
Trends in parasitology - 1 Dec 2009
Escalante Ananias A, Smith David L, Kim Yuseob
Abstract excerpt
The evolution of resistance in Plasmodium falciparum against safe and affordable drugs such as chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) is a major global health threat. Investigating the dynamics of resistance against these antimalarial drugs will lead to approaches for addressing the problem of resistance in malarial parasites that are solidly based in evolutionary genetics and population biology. In...
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