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Article

MAP kinase signaling antagonizes PAR-1 function during polarization of the early Caenorhabditis elegans embryo.

Genetics - 1 Nov 2009

Spilker Annina C, Rabilotta Alexia, Zbinden Caroline, Labbé Jean-Claude, Gotta Monica

Abstract excerpt

PAR proteins (partitioning defective) are major regulators of cell polarity and asymmetric cell division. One of the par genes, par-1, encodes a Ser/Thr kinase that is conserved from yeast to mammals. In Caenorhabditis elegans, par-1 governs asymmetric cell division by ensuring the polar distribution of cell fate determinants. However the precise mechanisms by which PAR-1 regulates asymmetric cell division in C....

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Source

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Identifiers

PMID: 19720857
DOI: 10.1534/genetics.109.106716
PMCID: PMC2778991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MAP kinase signaling antagonizes PAR-1 function during polarization of the early Caenorhabditis elegans embryo.PMID 19720857Read ↗

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