PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos.

doi:10.1242/dev.122.10.3075

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Article

PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos.

Development (Cambridge, England) - 1 Oct 1996

Boyd L, Guo S, Levitan D, Stinchcomb D T, Kemphues K J

Abstract excerpt

The par genes participate in the process of establishing cellular asymmetries during the first cell cycle of Caenorhabditis elegans development. The par-2 gene is required for the unequal first cleavage and for asymmetries in cell cycle length and spindle orientation in the two resulting daughter...

Topics

Animals
Blastomeres
Caenorhabditis elegans
Caenorhabditis elegans Proteins
DNA-Binding Proteins
Helminth Proteins
Mutation
Protein Serine-Threonine Kinases
Saccharomyces cerevisiae Proteins

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