Article
par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.
Development (Cambridge, England) - 1 Oct 1996
Watts J L, Etemad-Moghadam B, Guo S, Boyd L, Draper B W, Mello C C, Priess J R, Kemphues K J
Abstract excerpt
The generation of asymmetry in the one-cell embryo of Caenorhabditis elegans is necessary to establish the anterior-posterior axis and to ensure the proper identity of early blastomeres. Maternal-effect lethal mutations with a partitioning defective phenotype (par) have identified several genes i...
Topics
- Alleles
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cleavage Stage, Ovum
- Drosophila
- Helminth Proteins
- Protein Serine-Threonine Kinases
- Suppression, Genetic