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Article

par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.

Development (Cambridge, England) - 1 Oct 1996

Watts J L, Etemad-Moghadam B, Guo S, Boyd L, Draper B W, Mello C C, Priess J R, Kemphues K J

Abstract excerpt

The generation of asymmetry in the one-cell embryo of Caenorhabditis elegans is necessary to establish the anterior-posterior axis and to ensure the proper identity of early blastomeres. Maternal-effect lethal mutations with a partitioning defective phenotype (par) have identified several genes involved in this process. We have identified a new gene, par-6, which acts in conjunction with other par genes to...

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PMID: 8898226
DOI: 10.1242/dev.122.10.3133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.PMID 8898226Read ↗

The Caenorhabditis elegans par-5 gene encodes a 14-3-3 protein required for cellular asymmetry in the early embryo.Semantic proximity Read ↗

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The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos.Semantic proximity Read ↗

MAP kinase signaling antagonizes PAR-1 function during polarization of the early Caenorhabditis elegans embryo.Semantic proximity Read ↗

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The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo.Semantic proximity Read ↗

The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry.Semantic proximity Read ↗

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RAB-5 controls the cortical organization and dynamics of PAR proteins to maintain C. elegans early embryonic polarity.Semantic proximity Read ↗

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