Article
Complement 3 is involved in the synthetic phenotype and exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 2004
Lin Zhi-Hong, Fukuda Noboru, Jin Xue-Qing, Yao En-Hui, Ueno Takahiro, Endo Morito, Saito Satoshi, Matsumoto Koichi, Mugishima Hideo
Abstract excerpt
Vascular smooth muscle cells (VSMCs) from spontaneously hypertensive rats (SHR) show the synthetic phenotype and exaggerated growth in comparison with VSMCs from normotensive Wistar-Kyoto (WKY) rats. We investigated genes associated with the synthetic phenotype and exaggerated growth of VSMCs from SHR by microarray. Expression of 1300 transcripts was evaluated by microarray with total mRNA extracted from...
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