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Article

RNO3 QTL regulates vascular structure and arterial stiffness in the spontaneously hypertensive rat.

Physiological genomics - 1 Dec 2021

Morgan Eric E, Morran Michael P, Horen Nicholas G, Weaver David A, Nestor-Kalinoski Andrea L

Abstract excerpt

Increased arterial stiffness is an independent risk factor for hypertension, stroke, and cardiovascular morbidity. Thus, understanding the factors contributing to vascular stiffness is of critical importance. Here, we used a rat model containing a known quantitative trait locus (QTL) on chromosome 3 (RNO3) for vasoreactivity to assess potential genetic elements contributing to blood pressure, arterial stiffness,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34755572
DOI: 10.1152/physiolgenomics.00038.2021
PMCID: PMC9275012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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