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Article

CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2010

Shimoyama Tatsushi, Hiraoka Shûichi, Takemoto Minoru, Koshizaka Masaya, Tokuyama Hirotake, Tokuyama Takahiko, Watanabe Aki, Fujimoto Masaki, Kawamura Harukiyo, Sato Seiya, Tsurutani Yuya, Saito Yasushi, Perbal Bernard, Koseki Haruhiko, Yokote Koutaro

Abstract excerpt

OBJECTIVE: CCN3 belongs to the CCN family, which constitutes multifunctional secreted proteins that act as matrix cellular regulators. We investigated the pathophysiological roles of CCN3 in the vessels. METHODS AND RESULTS: We examined the effects of CCN3 on the proliferation and migration of ra...

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Source

Identifiers

PMID: 20139355
DOI: 10.1161/ATVBAHA.110.203356

Genes

CCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20139355-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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