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Article

Novel mechanisms of the antiproliferative effects of amlodipine in vascular smooth muscle cells from spontaneously hypertensive rats.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2002

Lai Yi-Mu, Fukuda Noboru, Su Jin-Zi, Suzuki Ryo, Ikeda Yukihiro, Takagi Hiroto, Tahira Yoshiko, Kanmatsuse Katsuo

Abstract excerpt

The calcium channel blocker amlodipine continues to be of interest due to its potential proven ability to hinder the progression of atherosclerosis and reduce the number of clinical ischemic events. Vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) are useful in the study of atherosclerosis because they show exaggerated growth with production of angiotensin II (Ang II) by conversion...

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Source

Identifiers

PMID: 11924715
DOI: 10.1291/hypres.25.109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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