Article
Contribution of synthetic phenotype on the enhanced angiotensin II-generating system in vascular smooth muscle cells from spontaneously hypertensive rats.
Journal of hypertension - 1 Aug 1999
Fukuda N, Hu W Y, Satoh C, Nakayama M, Kishioka H, Kubo A, Kanmatsuse K
Abstract excerpt
OBJECTIVE: We have demonstrated that cultured vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR), but not from normotensive Wistar-Kyoto (WKY) rats, produce angiotensin II (Ang II) in a homogeneous culture with increased levels of angiotensinogen, cathepsin D and angio...
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