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Article

Growth characteristics, angiotensin II generation, and microarray-determined gene expression in vascular smooth muscle cells from young spontaneously hypertensive rats.

Journal of hypertension - 1 Jul 2002

Hu Wen-Yang, Fukuda Noboru, Kanmatsuse Katsuo

Abstract excerpt

BACKGROUND: We have demonstrated that vascular smooth muscle cells (VSMCs) derived from spontaneously hypertensive rats (SHR) show exaggerated growth and produce angiotensin (Ang) II and growth factors. These may reflect intrinsic abnormalities in SHR that are not caused by excessive blood pressure, and are associated with genetic abnormalities. OBJECTIVE: To evaluate whether these characteristics of VSMCs from...

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Source

Identifiers

PMID: 12131529
DOI: 10.1097/00004872-200207000-00019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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