Null phenotype for cytochrome P450 2B2 in the rat results from a deletion of its structural gene.

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Article

Null phenotype for cytochrome P450 2B2 in the rat results from a deletion of its structural gene.

Molecular pharmacology - 1 Aug 1992

Omiecinski C J, Ramsden R, Rampersaud A, Walz F G

Abstract excerpt

The absence of phenobarbital (PB)-inducible cytochrome P450 2B2 (CYP2B2) in hepatic microsomes from Marshall 520 (M520) and Wistar Munich (WM) inbred strains of rat was previously reported [Biochem. Genet. 25:527-534 (1987)], and it was subsequently shown for M520 rats that corresponding CYP2B2 m...

Topics

Alleles
Animals
Base Sequence
Chromosome Deletion
Cytochrome P-450 Enzyme System
DNA
Enzyme Induction
Gene Amplification
Genes
Liver
Molecular Sequence Data
Nucleic Acid Hybridization
Phenobarbital
Phenotype
Polymerase Chain Reaction
RNA, Messenger
Rats
Rats, Inbred Strains

Source

Open in PubMed

Identifiers

PMID: 1513322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1513322-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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