Article
Characterization of CD8+ T cell repertoire diversity and persistence in the influenza A virus model of localized, transient infection.
Seminars in immunology - 1 Jun 2004
Turner Stephen J, Kedzierska Katherine, La Gruta Nicole L, Webby Richard, Doherty Peter C
Abstract excerpt
Influenza virus infection of C57BL/6 mice provides a well-characterized model for the study of acute CD8(+) T cell responses and for the analysis of memory in the absence of antigen persistence. The advent of tetramer reagents and intracellular cytokine staining, coupled with techniques such as single cell RT-PCR and influenza reverse genetics, has enabled the detailed molecular dissection of different...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.