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Article

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells.

Immunology and cell biology - 1 Nov 2018

Keating Rachael, Morris Melissa Y, Yue Wen, Reynolds Cory E, Harris Tarsha L, Brown Scott A, Doherty Peter C, Thomas Paul G, McGargill Maureen A

Abstract excerpt

Current influenza A virus (IAV) vaccines stimulate antibody responses that are directed against variable regions of the virus, and are therefore ineffective against divergent strains. As CD8+ T cells target the highly conserved, internal IAV proteins, they have the potential to increase heterosubtypic immunity. Early T-cell priming events influence lasting memory, which is required for long-term protection....

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Share to CD8-Positive T-Lymphocytes
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Interleukin-2 Receptor alpha Subunit

Share to Orthomyxoviridae Infections

Share to Protein Multimerization

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to T-Cell Antigen Receptor Specificity

Source

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Identifiers

PMID: 29972699
DOI: 10.1111/imcb.12189
PMCID: PMC6282960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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