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Article

In situ detection of apolipoprotein E epsilon 4 in archival human brain.

Neuroreport - 19 May 2004

Saito Yuko, Ruberu Nyoka N, Harada Mieko, Arai Tomio, Sawabe Motoji, Nukina Nobuyuki, Murayama Shigeo

Abstract excerpt

A monoclonal antibody specific to apolipoprotein E 4 (apoE4) was applied immunohistochemically to archival human brain tissue. The examined 30 cases comprised four epsilon/epsilon4, 10 epsilon3/epsilon4, one epsilon2/epsilon4, 10 epsilon3/epsilon3 and five epsilon2/epsilon3 genotypes. The anti apoE4 antibody visualized senile plaques, neurofibrillary tangles and reactive astrocytes, as well as serum in the blood...

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Source

Identifiers

PMID: 15129156
DOI: 10.1097/00001756-200405190-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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