Article
Apolipoprotein E genotype in diverse neurodegenerative disorders.
Annals of neurology - 1 Jul 1995
Schneider J A, Gearing M, Robbins R S, de l'Aune W, Mirra S S
Abstract excerpt
While the apolipoprotein E (ApoE) epsilon 4 allele is a recognized risk factor for Alzheimer's disease (AD), an association of epsilon 4 with other neurodegenerative diseases (NDs) has not been extensively explored. We examined 51 cases of neuropathologically confirmed ND. After eliminating 18 cases exhibiting pathology sufficient to warrant an additional diagnosis of AD, three disorders characterized by...
Topics
- Aged
- Alleles
- Apolipoproteins E
- Brain
- Genotype
- Humans
- Immunohistochemistry
- Nerve Degeneration
- Nervous System Diseases
