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Article

Identification of the region in Cdc42 that confers the binding specificity to activated Cdc42-associated kinase.

The Journal of biological chemistry - 16 Jul 2004

Gu Yan, Lin Qiong, Childress Chandra, Yang Wannian

Abstract excerpt

The Rho family small G-protein Cdc42 has been implicated in a diversity of biological functions. Multiple downstream effectors have been identified. How Cdc42 discriminates the interaction with its multiple downstream effectors is not known. Activated Cdc42-associated tyrosine kinase (ACK) is a very specific effector of Cdc42. To delineate the Cdc42 signaling pathway mediated by ACK, we set about to identify the...

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Identifiers

PMID: 15123659
DOI: 10.1074/jbc.M313518200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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