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Article

Isolation and characterization of effector-loop mutants of CDC42 in yeast.

Molecular biology of the cell - 1 May 2001

Gladfelter A S, Moskow J J, Zyla T R, Lew D J

Abstract excerpt

The highly conserved small GTPase Cdc42p is a key regulator of cell polarity and cytoskeletal organization in eukaryotic cells. Multiple effectors of Cdc42p have been identified, although it is unclear how their activities are coordinated to produce particular cell behaviors. One strategy used to address the contributions made by different effector pathways downstream of small GTPases has been the use of...

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Identifiers

PMID: 11359919
DOI: 10.1091/mbc.12.5.1239
PMCID: PMC34581

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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