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Article

Signaling role of Cdc42 in regulating mammalian physiology.

The Journal of biological chemistry - 28 Jan 2011

Melendez Jaime, Grogg Matthew, Zheng Yi

Abstract excerpt

Cdc42 is a member of the Rho GTPase family of intracellular molecular switches regulating multiple signaling pathways involved in actomyosin organization and cell proliferation. Knowledge of its signaling function in mammalian cells came mostly from studies using the dominant-negative or constitu...

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Identifiers

PMID: 21115489
DOI: 10.1074/jbc.R110.200329
PMCID: PMC3024731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21115489-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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