Article
Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase.
The EMBO journal - 2 Jan 1997
Leberer E, Wu C, Leeuw T, Fourest-Lieuvin A, Segall J E, Thomas D Y
Abstract excerpt
Ste20p from Saccharomyces cerevisiae belongs to the Ste20p/p65PAK family of protein kinases which are highly conserved from yeast to man and regulate conserved mitogen-activated protein kinase pathways. Ste20p fulfills multiple roles in pheromone signaling, morphological switching and vegetative growth and binds Cdc42p, a Rho-like small GTP binding protein required for polarized morphogenesis. We have analyzed...
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