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Article

Functional dimorphism of two hAgRP promoter SNPs in linkage disequilibrium.

Journal of medical genetics - 1 May 2004

Bai F, Rankinen T, Charbonneau C, Belsham D D, Rao D C, Bouchard C, Argyropoulos G

Abstract excerpt

The agouti related protein (AgRP) exerts its anabolic effects on food intake by antagonising the alpha-melanocyte stimulating hormone (alpha-MSH) at its receptors, melanocortin receptors 3 and 4 (MC3R and MC4R). A single nucleotide polymorphism (SNP) in the promoter of the human AgRP (hAgRP), -38C>T, was associated with low body fatness. The -38T allele that was associated with low body fatness also resulted in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15121772
DOI: 10.1136/jmg.2003.014092
PMCID: PMC1735766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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