Article
The gene structure and minimal promoter of the human agouti related protein.
Gene - 17 Oct 2001
Brown A M, Mayfield D K, Volaufova J, Argyropoulos G
Abstract excerpt
The murine agouti related protein (mAGRP) is upregulated in obese and diabetic mice and stimulates hyperphagia when administered intracerebroventricularly (i.c.v.) or when overexpressed in transgenic mice. The human ortholog, hAGRP, has been isolated and has similar molecular and physiological properties. Here, we report the complete gene structure of the human AGRP gene and upstream regions with differential...
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