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Article

The human involucrin gene is transcriptionally repressed through a tissue-specific silencer element recognized by Oct-2.

Biochemical and biophysical research communications - 28 May 2004

Azuara-Liceaga Elisa, Sandoval Marisol, Corona Matilde, Gariglio Patricio, López-Bayghen Esther

Abstract excerpt

Involucrin is an important marker of epithelial differentiation which expression is upregulated just after basal cells are pushed into the suprabasal layer in stratified epithelia. Several transcription factors and regulatory elements had been described as responsible for turning on the gene. However, it is evident that in basal cell layer, additional mechanisms are involved in keeping the gene silent before the...

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Identifiers

PMID: 15120610
DOI: 10.1016/j.bbrc.2004.04.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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