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Article

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.

Nucleic acids research - 1 May 2008

Kirschner Ralf D, Sänger Katja, Müller Gerd A, Engeland Kurt

Abstract excerpt

S100A2 is generally found expressed in the epidermis and was recently shown to play a crucial role in the differentiation of keratinocytes. Also known as CaN19, S100A2 was identified as a potential tumor suppressor. Expression of S100A2 is upregulated by p53. The proteins p63 and p73 are related to p53 and are expressed as several splice variants with partially overlapping tasks but also functions different from...

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Identifiers

PMID: 18388131
DOI: 10.1093/nar/gkn132
PMCID: PMC2396407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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