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Article

Regulation of basal core promoter activity of human organic cation transporter 1 (OCT1/SLC22A1).

American journal of physiology. Gastrointestinal and liver physiology - 1 Dec 2008

Kajiwara Moto, Terada Tomohiro, Asaka Jun-ichi, Aoki Masayo, Katsura Toshiya, Ikai Iwao, Inui Ken-ichi

Abstract excerpt

Human organic cation transporter 1 (OCT1/SLC22A1) plays important roles in the hepatic uptake of cationic drugs. The functional characteristics of this transporter have been well evaluated, but molecular information regarding transcriptional regulation is limited. In the present study, therefore, we examined the gene regulation of OCT1 gene focusing on basal core expression. An approximately 2.5-kb fragment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18845576
DOI: 10.1152/ajpgi.90360.2008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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