Article
Influence of a cap site element on tissue-restricted expression of the glycoprotein hormone alpha-subunit gene.
Biochemical and biophysical research communications - 14 Jul 1999
Cox G S, Xiong W
Abstract excerpt
Little is known of the transcriptional regulators important for expression of the glycoprotein hormone alpha-subunit (GPHalpha) gene in nonendocrine tumors, which secrete free alpha-subunit at an incidence of 25-80%. Consequently, attempts were made to define cis-regulatory elements and their cognate trans-acting factors that modulate promoter activity in epithelial cell types that do not normally express the...
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