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BanI polymorphism of the cytosolic phospholipase A2 gene and mood disorders in the Korean population.

Neuropsychobiology - 1 Jan 2004

Pae Chi-Un, Yu Hye-Sook, Kim Jung-Jin, Lee Chang-Uk, Lee Soo-Jung, Lee Kyoung-Uk, Jun Tae-Youn, Paik In-Ho, Serretti Alessandro, Lee Chul

Abstract excerpt

Membrane phospholipid abnormalities have been proposed to be involved in the pathogenesis of mood disorders, and in signal transduction and neurotransmitter uptake. Cytosolic phospholipase A2 (cPLA2) is not only an essential enzyme in the metabolism of fatty acids but also in signaling process. Therefore, we examined the association between the BanI polymorphism of the cPLA2 gene and mood disorders. Sixty-two...

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PMID: 15118355
DOI: 10.1159/000077364

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