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Article

Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.

Molecular biology reports - 1 Nov 2023

Aflouk Youssef, Inoubli Oumaima, Kenz Amira, Yacoub Saloua, Zaafrane Ferid, Gaha Lotfi, Bel Hadj Jrad Besma

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is a complex neuropsychiatric disease that has been strongly linked to immune dysregulation. In particular, an abnormal inflammatory response mediated by toll-like receptor 2 - 1/6 (TLR2-1/6) was described in BD. Nevertheless, genetic factors' contribution is still unknown. Thus, we suggested that functional polymorphisms of TLR2, 1 and 6 could be involved in BD predisposition....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37688680
DOI: 10.1007/s11033-023-08758-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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