Article
Association of the Ban I dimorphic site at the human cytosolic phospholipase A2 gene with schizophrenia.
Psychiatric genetics - 1 Jan 1998
Peet M, Ramchand C N, Lee J, Telang S D, Vankar G K, Shah S, Wei J
Abstract excerpt
There is evidence of increased phospholipid breakdown in cell membranes of patients suffering from schizophrenia. This may be related to increased levels of the enzyme cytosolic phospholipase A2 (cPLA2) which have been reported in schizophrenic subjects. We have identified a Ban I dimorphic site...
Topics
- Cytosol
- Deoxyribonucleases, Type II Site-Specific
- Genetic Predisposition to Disease
- Humans
- India
- Introns
- Isoenzymes
- Phospholipases A
- Phospholipases A2
- Polymorphism, Restriction Fragment Length
- Schizophrenia