Article
BanI polymorphism of the cytosolic phospholipase A2 gene may confer susceptibility to the development of schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2004
Pae Chi-Un, Yu Hye-Sook, Lee Kyoung-Uk, Kim Jung-Jin, Lee Chang-Uk, Lee Soo-Jung, Jun Tae-Youn, Lee Chul, Paik In-Ho
Abstract excerpt
Membrane phospholipid abnormalities have been proposed to be involved in the pathogenesis of schizophrenia. Cytosolic phospholipase A2 (cPLA2) plays a major role in the metabolism of fatty acids but is also found in abnormalities in patients with schizophrenia. This study examined the association between the cPLA2 gene BanI polymorphism and schizophrenia. Ninety-seven Korean schizophrenia patients and 117 healthy...
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