Article
BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Jun 2008
Nadalin S, Rubesa G, Giacometti J, Vulin M, Tomljanović D, Vraneković J, Kapović M, Buretić-Tomljanović A
Abstract excerpt
The enzymes phospholipases A2 are believed to be involved in the pathology of schizophrenia. We investigated allelic and genotype frequencies of PLA2G4A BanI polymorphism and the rs4375 in PLA2G6A in Croatian schizophrenic patients (n=81) and controls (n=182), using PCR/RFLP. Genotype and allelic frequencies of both loci, alone or in combination did not show significant difference (chi2-test). Allele-wise and...
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