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Article

Association between alcoholism and the gene encoding the endocannabinoid synthesizing enzyme diacylglycerol lipase alpha in the Japanese population.

Alcohol (Fayetteville, N.Y.) - 1 May 2018

Ishiguro Hiroki, Higuchi Susumu, Arinami Tadao, Onaivi Emmanuel S

Abstract excerpt

The endocannabinoid system has been recognized to be involved in neuropsychiatric diseases. 2-arachidonoyl glycerol (2-AG) is one of the two main endocannabinoids, and their regulation could play roles in disorders under environmental influence. This study investigated the involvement of the 2-AG biosynthesizing enzyme diacylglycerol lipase alpha (DAGLA) in the pathogenesis of alcoholism. We investigated a...

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Identifiers

PMID: 29477030
DOI: 10.1016/j.alcohol.2017.09.005

Genes

DAGLA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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