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Article

A monomeric human apolipoprotein E carboxyl-terminal domain.

Biochemistry - 4 May 2004

Fan Daping, Li Qianqian, Korando Leslie, Jerome W Gray, Wang Jianjun

Abstract excerpt

ApoE plays a critical role in lipoprotein metabolism and plasma lipid homeostasis through its high-affinity binding to the LDL-receptor family. In solution, apoE is an oligomeric protein and the C-terminal domain causes apoE's aggregation. The aggregation property presents a major difficulty for the structural determination of this protein. A high-level expression system of the apoE C-terminal domain is reported...

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Source

Identifiers

PMID: 15109264
DOI: 10.1021/bi035958w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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