Article

Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides

2023-02-23

Abstract excerpt

<h4>Background</h4> Plasma triglycerides (TGs) are causally associated with coronary artery disease and acute pancreatitis. Apolipoprotein A-V (apoA-V, gene APOA5 ) is a liver-secreted protein that is carried on triglyceride-rich lipoproteins and promotes the enzymatic activity of lipoprotein lipase (LPL), thereby reducing TG levels. Little is known about apoA-V structure-function; naturally occurring human APOA5...

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Literature Corpus work: 0f893dfc-46eb-51a8-bec2-3990d18861d3
DOI: 10.1101/2023.02.21.23286268

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