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Article

Adult human mesenchymal stem cell as a target for neoplastic transformation.

Oncogene - 24 Jun 2004

Serakinci Nedime, Guldberg Per, Burns Jorge S, Abdallah Basem, Schrødder Henrik, Jensen Thomas, Kassem Moustapha

Abstract excerpt

The neoplastic process may involve a cancer stem cell. This concept has emerged largely from the careful analysis of tumour biopsy systems from haematological, breast and brain tumours. However, the experimental systems necessary to provide the cellular and molecular evidence to support this important concept have been lacking. We have used adult mesenchymal stem cells (hMSC) transduced with the telomerase hTERT...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15107831
DOI: 10.1038/sj.onc.1207651

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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