Article
hTERT promotes cell adhesion and migration independent of telomerase activity.
Scientific reports - 14 Mar 2016
Liu Haiying, Liu Qianqian, Ge Yuanlong, Zhao Qi, Zheng Xiaohui, Zhao Yong
Abstract excerpt
hTERT, a catalytic component of human telomerase, is undetectable in normal somatic cells but up-regulated in cancer and stem cells where telomere length is maintained by telomerase. Accumulated evidence indicates that hTERT may have noncanonical functions beyond telomerase by regulating the expression of particular genes. However, comprehensive identification of the genes regulated by hTERT is unavailable. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
