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Article

Transfer of malignant trait to immortalized human cells following exposure to human cancer serum.

Journal of experimental & clinical cancer research : CR - 30 Sept 2014

Abdouh Mohamed, Zhou Shufeng, Arena Vincenzo, Arena Manuel, Lazaris Anthoula, Onerheim Ronald, Metrakos Peter, Arena Goffredo Orazio

Abstract excerpt

BACKGROUND: Human cancer cells can transfer signaling molecules to neighboring and distant cells predisposing them to malignant transformation. This process might contribute to tumor progression and invasion through delivery of oncogenes or inhibitors of tumor suppressor genes, derived from the primary tumor cells, to susceptible target cells. The oncogenic potential of human cancer serum has been described in...

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Identifiers

PMID: 25266310
DOI: 10.1186/s13046-014-0086-5
PMCID: PMC4181828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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