Article
Tumor initiation via loss of cell contact inhibition versus Ras mutation: do all roads lead to EMT?
Cell cycle (Georgetown, Tex.) - 1 Mar 2010
Liu Yongqing, Dean Douglas C
Abstract excerpt
Many tumors have been found to contain a subset of cells referred to as cancer stem cells. As opposed to the remainder of the tumor, these cells are undifferentiated-they do not express markers of differentiation and they can re-express stem cell specification genes. The cells can divide asymmetrically to yield differentiated cells as well as cells comprising the original heterogeneous population of the tumor...
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