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Article

Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells.

American journal of physiology. Cell physiology - 1 Feb 2003

Alvarez de la Rosa Diego, Canessa Cecilia M

Abstract excerpt

The purpose of this study was to examine the role of the serum- and glucocorticoid-induced kinase (SGK) in the activation of the epithelial sodium channel (ENaC) by aldosterone, arginine vasopressin (AVP), and insulin. We used a tetracycline-inducible system to control the expression of wild-type (SGK(wt)(T)), constitutively active (S425D mutation; SGK(S425D)(T)), or inactive (K130M mutation; SGK(K130M)(T)) SGK...

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Source

Identifiers

PMID: 12388075
DOI: 10.1152/ajpcell.00398.2002

Genes

AVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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