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Article

A tamoxifen inducible knock-in allele for investigation of E2A function.

BMC developmental biology - 12 Oct 2009

Jones Mary E, Kondo Motonari, Zhuang Yuan

Abstract excerpt

BACKGROUND: E-proteins are transcription factors important for the development of a variety of cell types, including neural, muscle and lymphocytes of the immune system. E2A, the best characterized E-protein family member in mammals, has been shown to have stage specific roles in cell differentiation, lineage commitment, proliferation, and survival. However, due to the complexity of E2A function, it is often...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19822014
DOI: 10.1186/1471-213X-9-51
PMCID: PMC2765948

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