Article
Genetic analysis of soluble N-ethylmaleimide-sensitive factor attachment protein function in Drosophila reveals positive and negative secretory roles.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Apr 2004
Babcock Michael, Macleod Greg T, Leither Jennifer, Pallanck Leo
Abstract excerpt
The N-ethylmaleimide-sensitive factor (NSF) and soluble NSF attachment protein (SNAP) are cytosolic factors that promote vesicle fusion with a target membrane in both the constitutive and regulated secretory pathways. NSF and SNAP are thought to function by catalyzing the disassembly of a SNAP receptor (SNARE) complex consisting of membrane proteins of the secretory vesicle and target membrane. Although studies...
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