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Article

The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF.

The Journal of biological chemistry - 1 Jan 2000

Ramírez Juanma, Morales Miguel, Osinalde Nerea, Martínez-Padrón Imanol, Mayor Ugo, Ferrús Alberto

Abstract excerpt

Ariadne-1 (Ari-1) is an E3 ubiquitin-ligase essential for neuronal development, but whose neuronal substrates are yet to be identified. To search for putative Ari-1 substrates, we used an in vivo ubiquitin biotinylation strategy coupled to quantitative proteomics of Drosophila heads. We identified 16 candidates that met the established criteria: a significant change of at least twofold increase on ubiquitination,...

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Identifiers

PMID: 33581113
DOI: 10.1016/j.jbc.2021.100408
PMCID: PMC7960542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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