Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular mechanisms determining conserved properties of short-term synaptic depression revealed in NSF and SNAP-25 conditional mutants.

Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009

Kawasaki Fumiko, Ordway Richard W

Abstract excerpt

Current models of synaptic vesicle trafficking implicate a core complex of proteins comprised of N-ethylmaleimide-sensitive factor (NSF), soluble NSF attachment proteins (SNAPs), and SNAREs in synaptic vesicle fusion and neurotransmitter release. Despite this progress, major challenges remain in establishing the in vivo functions of these proteins and their roles in determining the physiological properties of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evoked Potentials
Share to Excitatory Postsynaptic Potentials

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuromuscular Junction

Share to Qa-SNARE Proteins

Share to SNARE Proteins

Share to Synapses

Share to Synaptic Vesicles

Share to Synaptosomal-Associated Protein 25

Source

Open in PubMed Open full text

Identifiers

PMID: 19706552
DOI: 10.1073/pnas.0907144106
PMCID: PMC2732793

Genes

NSF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular mechanisms determining conserved properties of short-term synaptic depression revealed in NSF and SNAP-25 conditional mutants.PMID 19706552Read ↗

Developmentally regulated switch in alternatively spliced SNAP-25 isoforms alters facilitation of synaptic transmission.Semantic proximity Read ↗

Snapin facilitates the synchronization of synaptic vesicle fusion.Semantic proximity Read ↗

Genetic analysis of soluble N-ethylmaleimide-sensitive factor attachment protein function in Drosophila reveals positive and negative secretory roles.Semantic proximity Read ↗

Differential roles for snapin and synaptotagmin in the synaptic vesicle cycle.Semantic proximity Read ↗

Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses.Semantic proximity Read ↗

A screen for genes that regulate synaptic growth reveals mechanisms that stabilize synaptic strengthSemantic proximity Read ↗

A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission.Semantic proximity Read ↗

Opposing functions of two sub-domains of the SNARE-complex in neurotransmission.Semantic proximity Read ↗

Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction.Semantic proximity Read ↗

Activity-dependent interactions of NSF and SNAP at living synapses.Semantic proximity Read ↗

SNARE interactions in membrane trafficking: a perspective from mammalian central synapses.Semantic proximity Read ↗

Abnormal Presynaptic Short-Term Plasticity and Information Processing in a Mouse Model of Fragile X SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.