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Article

Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila.

Molecular biology of the cell - 1 Nov 2006

Nunes Paula, Haines Nicola, Kuppuswamy Venkat, Fleet David J, Stewart Bryan A

Abstract excerpt

N-ethylmaleimide sensitive factor (NSF) can dissociate the soluble NSF attachment receptor (SNARE) complex, but NSF also participates in other intracellular trafficking functions by virtue of SNARE-independent activity. Drosophila that express a neural transgene encoding a dominant-negative form of NSF2 show an 80% reduction in the size of releasable synaptic vesicle pool, but no change in the number of vesicles...

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Identifiers

PMID: 16914524
DOI: 10.1091/mbc.e06-03-0253
PMCID: PMC1635382

Genes

NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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