Article
Enhancement of host fitness by the sul2-coding plasmid p9123 in the absence of selective pressure.
The Journal of antimicrobial chemotherapy - 1 Jun 2004
Enne Virve I, Bennett Peter M, Livermore David M, Hall Lucinda M C
Abstract excerpt
OBJECTIVES: Despite a 97% reduction in clinical sulphonamide usage, the prevalence of sulphonamide resistance among Escherichia coli has remained constant in the UK. Genetic linkage of sulphonamide resistance to other resistances is thought important for this maintenance, but the finding also implies that sulphonamide resistance exerts little fitness cost. To test this hypothesis, we examined the fitness impact...
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